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Three Dimensional Structure
of a Toxin: a-hemolysin from Staphylococcus
aureus
Ribbon diagram of the a-toxin of S. aureus. Reference. The b-barrel stalk of this mushroom-shaped protein inserts across succepible membranes and caused lethal permeability changes in the membrane by virtue of the toxins central pore. This molecule is a homo-heptamer, composed of 7 identical subunits. It is probably a member of a widespread class of similar toxin molecules, including aerolysin, leukocidin, the Anthrax protective antigen and others. |
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Top view of the same molecule. Notice the
pore through the middle of the structure.
PDB acess code 2AHL |
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