Interesting Membrane Proteins



 
Three Dimensional Structure of a Porin

Ribbon diagram of a porin from Rhodobacter capsulatus, refined at 1.8.  Reference. This is a good example of the b-barrel folding motif. 

Porins are a widespread class of bacterial outer membrane proteins and most are involved in transport of small molecules across the outer membrane. Porin-like proteins have also been identified in mitochondria and chloroplasts. 

The 3D structures are known for  of porin-like molecules having 8,16, 18 and 22 membrane-spanning b-strands. This porin has 16 strands.

Top view of the same molecule in a ribbon diagram and in CPK form. Notice the pore through the middle of the structure. 
 
 
 
 
 
 

PDB acess code 2POR 
 

Get PDB file for this molecule


 


Bill Wimley's Research
Biochemistry Faculty Research
Tulane Biochemistry Home