DR. O'CONNOR'S RESEARCH GROUP


RECENT PEER-REVIEWED PUBLICATIONS AND PATENTS

Publications:

H Song, S Jain, RM Enmon and KC O'Connor. Restructuring dynamics of DU 145 and LNCaP prostate cancer spheroids. In Vitro Cell Dev Biol - Anim, 40: 262-7 (2004).

C Vidulescu, S Clejan and KC O'Connor*. Vesicle traffic through intercellular bridges in DU 145 human prostate cancer cells. J Cell Mol Med, 8: 388-96 (2004).

H Song, O David, S Clejan, CL Giordano, H Pappas-LeBeau, L Xu and KC O'Connor*. Spatial composition of prostate cancer spheroids in mixed and static cultures. Tissue Eng, 10: 1266-76 (2004).

H Song, KC O'Connor*, DJ Lacks, RM Enmon and SK Jain. Monte Carlo simulation of LNCaP human prostate cancer cell aggregation in liquid-overlay culture. Biotechnol Prog, 19: 1742-9 (2003).

KC O'Connor*, H Song, N Rosenzweig and DA Jansen. Extracellular matrix substrata alter adipocyte yield and lipogenesis in primary cultures of stromal-vascular cells from human adipose. Biotechnol Lett, 25: 1967-72 (2003).

H Song, KC O'Connor*, O David, CL Giordano, H Pappas-LeBeau and S Clejan. Immunohisto-chemical analysis of differentiation in mixed and static prostate cancer spheroids. J Cell Mol Med, 7: 180-6 (2003).

RM Enmon, KC O'Connor, H Song, DJ Lacks and DK Schwartz.
Aggregation kinetics of well and poorly differentiated human prostate cancer cells. Biotechnol Bioeng, 80: 580-8 (2002). BB02.pdf

KC O'Connor, NL Cowger, DCR De Kee and RP Schwarz.
Prolonged shearing of insect cells in a Couette bioreactor. Enzyme Microb Technol, 31: 600-8  (2002). EMT02.pdf

H Song, KC O'Connor, KD Papadopoulos and DA Jansen. Differentiation kinetics of in vitro 3T3-L1 preadipocyte cultures. Tissue Eng, 8:1071-81 (2002). TE8VN6.pdf

Sanda Clejan, Kim O'Connor and Nitsa Rosenzweig, "Tri-Dimensional Prostate Cell Cultures in Simulated Microgravity and Induced Changes in Lipid Second Messengers and Signal Transduction," J. Cell. Mol. Med., 5, 60-73 (2001).

Nadim J. Hallab, Kirk J. Bundy, Kim O'Connor, Randy L. Moses and Joshua J. Jacobs, "Evaluation of Metallic and Polymeric Biomaterial Surface Energy and Surface Roughness Characteristics for Directed Cell Adhesion," Tissue Eng., 7, 55-71 (2001). TissEng01.pdf

Richard M. Enmon, Kim C. O'Connor, Daniel J. Lacks, Daniel K. Schwartz and Robert S. Dotson, "Dynamics of Spheroid Self-Assembly in Liquid-Overlay Culture of DU 145 Human Prostate Cancer Cells, " Biotechnol. Bioeng., 72, 579-591 (2001).  BB01.pdf

James W. Muhitch, Kim C. O'Connor, Diane A. Blake, Daniel J. Lacks, Nitsa Rosenzweig and Glenn F. Spaulding, "Characterization of Aggregation and Protein Expression of Bovine Corneal Endothelial Cells as Microcarrier Cultures in a Rotating-Wall Vessel," Cytotechnology, 32, 253-263 (2000).

Nancy L. Cowger, Kim C. O'Connor, Tim G. Hammond, Daniel J. Lacks and Gabriel L. Navar, "Characterization of Biomodal Cell Death of Insect Cells in a Rotating-Wall Vessel and Shaker Flask," Biotechnol. Bioeng., 64, 14-26 (1999). BB99.pdf

Review:
 Kim C. O'Connor, "Three-Dimensional Cultures of Prostatic Cells: Tissue Models for the Development of Novel Anti-Cancer Therapies," Pharm. Res., 16, 486-493 (1999). PharmRes99.pdf

Patents:
 Kim C. O'Connor, Glenn F. Spaulding, Thomas J. Goodwin, Laurie A. Aten, Karen M. Francis, Delmar R. Caldwell, Tacey L. Prewett and Wendy S. Fitzgerald, "Three-Dimensional Optic Tissue Culture and Process," United States Patent 5,962,324 (1999).

GF Spaulding, TJ Goodwin, KC O'Connor, KM Francis, AD Andrews and TL Prewett, Recombinant protein production and insect cell culture and process. US Patent 5,637,477 (1997).
 

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