Current Funding through 2008

K01 - NIMH/NIH
"Potassium Channel modulation in plasticity"

COBRE sub award (in collaboration with PI Nick Bazan)
Selected Publications

1: Ren Y, Barnwell LF, Alexander JC, Lubin FD, Adelman JP, Pfaffinger PJ,
Schrader LA, Anderson AE.
Regulation of surface localization of the small conductance Ca2+-activated
potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein
kinase.

J Biol Chem. 2006 Apr 28;281(17):11769-79. Epub 2006 Mar 2.


2: Schrader LA, Birnbaum SG, Nadin BM, Ren Y, Bui D, Anderson AE, Sweatt JD.
ERK/MAPK regulates the Kv4.2 potassium channel by direct phosphorylation of the
pore-forming subunit.

Am J Physiol Cell Physiol. 2006 Mar;290(3):C852-61. Epub 2005 Oct 26.


3: Birnbaum SG, Varga AW, Yuan LL, Anderson AE, Sweatt JD, Schrader LA.
Structure and function of Kv4-family transient potassium channels.
Physiol Rev. 2004 Jul;84(3):803-33. Review.


4: Varga AW, Yuan LL, Anderson AE, Schrader LA, Wu GY, Gatchel JR, Johnston D,
Sweatt JD.
Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and
upregulates neuronal A-type potassium currents.

J Neurosci. 2004 Apr 7;24(14):3643-54.


5: Schrader LA, Perrett SP, Ye L, Friedlander MJ.
Substrates for coincidence detection and calcium signaling for induction of
synaptic potentiation in the neonatal visual cortex.

J Neurophysiol. 2004 Jun;91(6):2747-64. Epub 2004 Feb 18.


6: Shibata R, Misonou H, Campomanes CR, Anderson AE, Schrader LA, Doliveira LC,
Carroll KI, Sweatt JD, Rhodes KJ, Trimmer JS.
A fundamental role for KChIPs in determining the molecular properties and
trafficking of Kv4.2 potassium channels.

J Biol Chem. 2003 Sep 19;278(38):36445-54. Epub 2003 Jun 26.


7: Schrader LA, Anderson AE, Mayne A, Pfaffinger PJ, Sweatt JD.
PKA modulation of Kv4.2-encoded A-type potassium channels requires formation of a
supramolecular complex.

J Neurosci. 2002 Dec 1;22(23):10123-33.


8: Schrader LA, Anderson AE, Varga AW, Levy M, Sweatt JD.
The other half of Hebb: K+ channels and the regulation of neuronal excitability
in the hippocampus.

Mol Neurobiol. 2002 Feb;25(1):51-66. Review.


9: Tasker JG, Boudaba C, Schrader LA.
Local glutamatergic and GABAergic synaptic circuits and metabotropic glutamate
receptors in the hypothalamic paraventricular and supraoptic nuclei.

Adv Exp Med Biol. 1998;449:117-21.


10: Schrader LA, Tasker JG.
Modulation of multiple potassium currents by metabotropic glutamate receptors in
neurons of the hypothalamic supraoptic nucleus.

J Neurophysiol. 1997 Dec;78(6):3428-37.


11: Schrader LA, Tasker JG.
Presynaptic modulation by metabotropic glutamate receptors of excitatory and
inhibitory synaptic inputs to hypothalamic magnocellular neurons.

J Neurophysiol. 1997 Feb;77(2):527-36.
Schrader Lab - Tulane University
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