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MEDICAL PROTOZOOLOGY (TRMD 607)

This is a comprehensive course covering protozoa which infect humans. The basic biology of these protozoa, as well as the clinical manifestations of the diseases they cause, will be discussed. Life cycles, morphological features, host-parasite interactions, geographical distribution, reservoir hosts, methods of transmission and control, pathology, immunological aspects and diagnosis will be covered. The biological and clinical perspectives gained in this course will assist students in the recognition, evaluation and management of public health problems or clinical practice involving medically important protozoa.

Lectures will be given on Wednesday and Friday afternoons during Session I (August 27-October 15) at 1:00-3:00 in Tidewater 1208 (see class schedule for room assignment updates and call numbers and see #4 on map for location of Tidewater Building).

2008 FALL SEMESTER SCHEDULE

Date Lecture Topics Chapters Text
Aug 27   What are Protozoa? 1-6
      Protozoan Cell and Molecular Biology    
  29   Giardiasis 3 7-11
      Other lumenal protozoa (Trichomoniasis, Balantidiosis, Blastocystis, Dientamoeba) 5-6 46-49, 92-93, 100
Sept 3   Amebiasis  4 84-89
  5   African Trypanosomiasis  8 32-37
  10   Chagas' Disease  9 39-44
  12   Leishmaniasis  10 13-30
  17   Midterm Exam    
  19   Plasmodium 15 50-57
      Malaria 59-67
  24   Pathophysiology of Malaria 57-59
      Epidemiology and Transmission of Malaria 65-67 
  26   Distinguishing Plasmodium species 60-65
      Chemotherapy and Drug Resistance 308-313
Oct 1   Coccidia 12-13  69-72, 96-98
  3   Toxoplasma 14 75-81
      Rare Apicomplexan Infections (Babesia, Sarcocystis) 16 95-96
  8   Free-Living Protozoa 17 98-100
  10   Opportunistic Infections and AIDS    
      Intracellular Pathogens 11   
  15   Comprehensive Final Examination    
       

Lecture links are to Study Guides. Chapters refer to draft chapters available on Blackboard. Text refers to corresponding pages in Parasitic Diseases, 5th edition by Despommier, Gwadz, Hotez and Knirsch, Apple Trees Productions, New York, 2005. Additional course related material and powerpoint files are available on Blackboard. PDF file of class syllabus.

Instructor: Mark F. Wiser, Ph.D.
Room 2224 Tidewater
988-2507
wiser@tulane.edu
Office Hours: Tues & Thurs 2-4 (or by appointment)

Supplemental Texts on reserve in the Medical School Library located on the second floor of the Medical School (1430 Tulane Avenue, see #1 on map).

Atlas of Human Parasitology, 4th edition, by Ash and Orihel. ASCP Press, 1997.

Color Atlas of Tropical Medicine and Parasitology by Peters and Gilles. Mosby-Wolfe, 1995.

Basic Clinical Parasitology, 6th ed. by Neva and Brown. Appleton & Lange, 1994.

Parasitic Diseases, 4th ed. by Despommier, Gwadz, Hotez and Knirsch. Apple Trees Production, 2000.

Human Parasitology, 2nd ed. by Bogitsh and Cheng. Academic Press, 1998.

Markell and Voge's Medical Parasitology, 8th ed. by Markell, John, and Krotoski. Saunders, 1999.

Protozoal Diseases, edited by Herbert M. Gilles. Oxford University Press, 1999.

Tropical Infectious Diseases: Principles, Pathogens, and Practice, by Guerrant, Walker, and Weller. Churchill Livingstone, 1999.

Essentials of Tropical Infectious Diseases, by Guerrant, Walker and Weller. Churchill Livingstone, 2001.

The CDC provide a free CD on the identification and diagnosis of parasites of public health concern. The CD contains information and images of many parasites with an emphasis on intestinal parasites. Go to http://www.dpd.cdc.gov/dpdx/HTML/Training.htm for more information.

Exams and Grades

A midterm and a comprehensive final exam will be given over the lecture material. The format of these lecture exams will be multiple choice, true/false, fill-in-the-blank. Grading is as follows:

Midterm Exam 80 points Key to Midterm Exam
Final Exam 120 points Key to Final Exam

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These pages are developed and maintained by Mark F. Wiser, Tulane University (©1999). Last update on October 23, 2008 .