GBCH 718- Biochemical Genetics

Spring 2001

Tuesday and Thursday: 1-3

Room 6301

Course Director: Arthur J. Lustig, Ph.D.
 
DATE
TUESDAY
  DATE
THURSDAY
      Jan. 11 Introduction to course 

Arthur Lustig, Ph.D.

Jan. 16 Recombination 1
Recombinational Models

Prescott Deininger, Ph.D.

  Jan. 18 Recombination 2
Recombinational Models
 

Prescott Deininger, Ph.D.

Jan. 23 Recombinatiion 3
Transposition

Prescott Deininger, Ph.D.

  Jan. 25 Recombination 4
Transposition 

Prescott Deininger, Ph.D.

Jan. 30 Genomic Instability 1 Prescott Deininger, Ph.D.***   Feb. 1 Genetic Instability 2

Prescott Deininger, Ph.D.***

Feb. 6 Eukaryotic Mitotic Recombination***

Arthur Lustig, Ph.D.

  Feb. 8 Eukaryotic Mitotic Recombination***

Arthur Lustig, Ph.D.

Feb. 13 DNA Replication 1:
An Overview

Jim Karam, Ph.D.

  Feb. 15 DNA Replication 2:
Origins and Initiation

Jim Karam, Ph.D.

Feb. 20 DNA Replication 3:
Origins and Initiation

Jim Karam, Ph.D.

  Feb. 22 DNA Replication 4:
Elongation Complexes

Jim Karam, Ph.D.

Feb. 29 Mardi Gras   March 1  Mardi Gras
March 6  DNA Replication 5:
Crosstalk between DNA Replication, Transcription and Translation

Jim Karam, Ph.D.***

  March 8 DNA Replicatin 6:
DNA Replication in the Cell Cycle

Jim Karam, Ph.D.***

March 13 DNA Replication-The End of Replication

Arthur Lustig, Ph.D.

March 15 DNA Repair 1

Chuck Miller, Ph.D.

March 20 EXAM   March 22 DNA Repair 2

Chuck Miller, Ph.D.

March 27 Reg 1-Prokaryotic
 

Michael Schurr, Ph.D.

  March 29 Reg 2-Prokaryotic
 

Michael Schurr, Ph.D.

April 3 Transcriptional Reg 3-Prokaryotic
 

Michael Schurr, Ph.D.

  April 5 Transcriptional Reg 4
Eukaryotic-Basic Elements

Arthur Lustig, Ph.D.

April 10 Transcriptional Reg 5

Silencer & Insulators***

Arthur Lustig, Ph.D.

  April 12 Transcriptional Reg 6

High Order Chromatin Structure***

Arthur Lustig, Ph.D.

April 18 Transcriptional Control

Transcriptional Termination

Mary Clancy, Ph.D.

  April 20 Transcriptional Control 2

Transcriptional Termination

Mary Clancy, Ph.D.

April 25 Post Transcriptional Control Polyadenylation

Mary Clancy, Ph.D.

April 27 Post-Transcriptional Control Polyadenylation

Mary Clancy, Ph.D.

MAY 2 EXAM WEEK   MAY 4 EXAM WEEK

GBCH 718- Biochemical Genetics

Tuesday and Thursday: 1-3

Room 6301

Course Director: Arthur J. Lustig, Ph.D.
 
 

This course emphasizes the critical analysis of manuscripts and solutions to experimental problems in molecular genetics, as well as a an reinforcement of some of the more advanced topics in geneitcs and molecular biology. There are four sections to this course: DNA Dynamics, DNA Replication, Transcriptional Control, and Higher Order Transcriptional and Post-Translational Control. One week prior to discussion of the papers (led by one of the students), students will be given the paper to be discussed on the Tuesday and Thursday of the subsequent week. The course instructor will act more as a facilitator than a didactic lecturer.

We will require that each student purchase An Introduction to Genetic Analysis, available in mid-December. The section dealing with the topic must be thoroughly read by the student prior to the Discussion groups.

Instructors of Section 1-Jan.16-Feb.8: Prescott Deininger, Ph.D., & Arthur Lustig, Ph.D.

Instructors of Section 2 (Feb.13-Mar.22): Jim Karam, Ph.D., Charles Miller, Ph.D. & Arthur Lustig, Ph.D.

Instructor of Section 3 (March 27-April 12): Michael Schurr, Ph.D. & Arthur J. Lustig, Ph.D.

Instructor of Section 4: (April 18- April 27): Mary Clancy, Ph.D.

1. Style

Individual and group--role as a facilitator--there is a course text which is An Introduction to Genetic Analysis and specific review articles-these are meant as background.

2. Grading

Based on individual performance in groups

Exams that ask students to analyze data--after each section
 
 

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