MEDICAL PROTOZOOLOGY (TRMD 607)

This is a comprehensive course covering protozoa which infect humans. The basic biology of these protozoa, as well as the clinical manifestations of the diseases they cause, will be discussed. Life cycles, morphological features, host-parasite interactions, geographical distribution, reservoir hosts, methods of transmission and control, pathology, immunological aspects and diagnosis will be covered. Laboratory exercises will focus on the identification and recognition of parasitic protozoa. The biological and clinical perspectives gained in this course will assist students in the recognition, evaluation and management of public health problems or clinical practice involving medically important protozoa.

Lectures will be given on Wednesday and Friday afternoons during Session II (October 19-December 14) at 12:00-2:00 in Tidewater 1210 (see class schedule for room assignment updates and call numbers). Two laboratory sections follow the lectures: Section-01 (2:00-3:30) and Section-02 (3:30-5:00). The teaching laboratory is located in room 2345 of the Tidewater Building (see #4 on map).

Additional links to on-line material supplementing the course include: Study Guides, Handouts, and Powerpoint Presentations. Additional course related material will also be available on Blackboard. Links to the study guides and powerpoint presentation associated with each particular lecture are available through the lecture title and PPS button (), respectively, in the schedule below. PDF file of class syllabus.

Date			Lecture Topics		Text	Laboratory Exercises
Oct	19		What are Protozoa?		1-6	Distribute Microscopes and Slide Boxes
			Protozoan Cell and Molecular Biology
	24		African Trypanosomiasis		32-37	African Trypanosomes
	26		Chagas' Disease		39-44	Trypanosoma cruzi
	31		Leishmaniasis		13-30	Leishmania
Nov	2		Free-Living Protozoa		98-100	Quiz
			Opportunistic Fungi
	7		Giardiasis		7-11	Giardia
			Trichomoniasis		46-49	Trichomonas and other flagellates
			Balantidiosis		92-93	Balantidium coli
	9		Amebiasis		84-89	Entamoeba histolytica
	14		Midterm Exam			Intestinal ameba, Blastocystis
			Non-Pathogenic Intestinal Ameba		100-104
	16		Plasmodium		50-57	Quiz
			Malaria		59-67
	28		Pathophysiology of Malaria		57-59	Free-living Ameba, Opportunistic fungi
			Chemotherapy and Drug Resistance		308-313
	30		Distinguishing Plasmodium species		60-65	Plasmodium
			Babesia		95-96	Babesia
	5		Coccidia		69-72, 96-98	Intestinal Coccidia
			Sarcocystis			Sarcocystis
	7		Toxoplasma		75-81	Toxoplasma
			Intracellular Pathogens
	14		Comprehensive Final Examinations.

On-line material to supplement the lectures include: Study Guides and Powerpoint Presentations. PDF file of class syllabus.

Supplemental Texts on reserve in the Medical School Library located on the second floor of the Medical School (1430 Tulane Avenue, see #1 on map).

Atlas of Human Parasitology, 4^th edition, by Ash and Orihel. ASCP Press, 1997.

Color Atlas of Tropical Medicine and Parasitology by Peters and Gilles. Mosby-Wolfe, 1995.

Basic Clinical Parasitology, 6th ed. by Neva and Brown. Appleton & Lange, 1994.

Parasitic Diseases, 4th ed. by Despommier, Gwadz, Hotez and Knirsch. Apple Trees Production, 2000.

Human Parasitology, 2nd ed. by Bogitsh and Cheng. Academic Press, 1998.

Markell and Voge's Medical Parasitology, 8th ed. by Markell, John, and Krotoski. Saunders, 1999.

Protozoal Diseases, edited by Herbert M. Gilles. Oxford University Press, 1999.

Tropical Infectious Diseases: Principles, Pathogens, and Practice, by Guerrant, Walker, and Weller. Churchill Livingstone, 1999.

Essentials of Tropical Infectious Diseases, by Guerrant, Walker and Weller. Churchill Livingstone, 2001.

The CDC provide a free CD on the identification and diagnosis of parasites of public health concern. The CD contains information and images of many parasites with an emphasis on intestinal parasites. Go to http://www.dpd.cdc.gov/dpdx/HTML/Training.htm for more information.